Top Healthcare ETFs

Last Updated: 1/17/2026

Our combined factor score ranks all ETFs using a combination of value, momentum, quality, and low volatility. The ETFS with the highest scores and the greatest consistency across the factors will receive the best rankings.

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Healthcare ETFs with the Highest Score Using Our Multi-Factor System

Ticker	ETF Name	Total Assets	Expense Ratio	Total Holdings	Active Share vs. S&P 500	Active Fee	Active Share vs. Russell 2000	Size Exposure	Value Exposure	Quality Exposure	Multi-Factor Exposure	Low Volatility Exposure
FTXH	First Trust Nasdaq Pharmaceuticals ET	$21,875,870	0.60%	51	99.83%	0.60%	96.53%	51	54	54	97	91
PPH	VanEck Pharmaceutical ETF	$1,213,806,000	0.36%	27	99.88%	0.36%	99.70%	23	54	85	97	97
PJP	Invesco Dynamic Pharmaceuticals ETF	$273,397,300	0.57%	24	99.96%	0.57%	99.05%	63	56	43	93	88
FXH	First Trust Health Care AlphaDEX ETF	$943,194,400	0.62%	82	100.00%	0.62%	100.00%	50	61	55	90	65
FHLC	Fidelity MSCI Health Care Index ETF	$3,026,770,000	0.08%	329	100.00%	0.08%	93.20%	61	37	71	89	90
PBE	Invesco Dynamic Biotech &Genome ETF	$243,337,300	0.58%	31	100.00%	0.58%	98.46%	67	30	47	89	51
IXJ	iShares S&P Global Healthcare Index Fund ETF	$3,818,633,000	0.42%	128	100.00%	0.42%	99.69%	30	41	77	88	96
XLV	SPDR Health Care Select Sector SPDR Fund	$38,918,500,000	0.10%	66	99.67%	0.10%	99.83%	32	45	88	86	96
IHE	iShares Dow Jones U.S. Pharmaceutical Index Fund ETF	$935,726,700	0.40%	38	100.00%	0.40%	97.77%	62	34	58	84	89
IYH	iShares Dow Jones U.S. Health Care Index Fund ETF	$3,581,775,000	0.40%	116	100.00%	0.40%	100.00%	41	38	88	82	93

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